Although malocclusion is inherently three-dimensional, transverse discrepancies have historically received less attention than sagittal and vertical problems. In recent years, however, the transverse dimension has gained increasing prominence in both clinical practice and research, driven by advances in diagnostic imaging, expanding treatment modalities, and a better understanding of the envelope of discrepancy. This presentation reviews recent trends in the assessment and management of transverse malocclusion and examines how current evidence translates into clinical decision-making. It will discuss contemporary diagnostic approaches, the biological and biomechanical basis of transverse correction, and the evolving role of treatment options such as conventional and skeletal-assisted expansion. By integrating current research with clinical reality, the presentation aims to clarify the indications, limitations, and expected outcomes of available therapies for transverse discrepancies.